Company:  Confidential

Job Title: Staff cryoelectron microscopist

Job Number: 87162

Location: New York, US

Job Description

Staff cryoelectron microscopist position

The Simons Electron Microscopy Center (SEMC) is a global leader in cryoelectron microscopy (cryoEM) and provides expertise and resources for understanding both molecular and cellular structures. The facilities include 15 transmission electron microscopes, four dual-beam and/or scanning electron microscopes, a full suite for Cryo Correlative Microscopy and a dedicated computational infrastructure for data analysis and structural determination. SEMC serves the nine member institutions of NYSBC, provides access and training to the national research community through the NIH National Center for CryoEM Access and Training, provides sample preparation and access and training for in situ cryoET through the NIH National Center for In-situ Tomographic Ultramicroscopy, and includes the Simons Machine Learning Center where a team of machine learning, computer vision, and computational biology experts are pushing the boundaries of machine learning and structural biology.

The New York Structural Biology Center (NYSBC) is a global leader in structural biology. The Center’s main facility comprises 50,000 square feet in Upper Manhattan and houses advanced instrumentation in Cryo-Electron Microscopy, Nuclear Magnetic Resonance Spectroscopy, and Protein Production. Its X-ray crystallographic facility is located at the National Synchrotron Light Source II at the Brookhaven National Laboratory. NYSBC is led by world leaders in structural biology and an outstanding staff of 50 researchers.

SEMC is seeking a staff cryoelectron microscopist to add to its electron microscopy operations team. The main duties of this position involve service and assisting our external and internal users make use of the scientific equipment at the center. Applicants must be able to work in a multi-tasking environment where priorities may change often and be able to work well with others. We currently operate a cryoEM sample preparation laboratory and several EM suites in NYC.

Along with a CV please include a cover letter with at least 3 references.

Responsibilities:

  • Day-to-day instrument operation, including image acquisition and microscope maintenance.
  • Training facility users in cryoEM technology.
  • Providing logistical support for day-to-day operations for users of the center.
  • Providing consultation to users on data and results obtained at the center.
  • Staffing at NYSBC locations for service.

Required Qualifications and Experience:

  • A science degree (Masters degree or above).
  • Strong communication skills (both verbal and written) are needed to interact professionally and effectively in the work environment such as the ability to read, write, comprehend, and discuss research materials.
  • Familiar working in a laboratory environment.
  • Comfortable around scientific instrumentation.
  • Basic computer skills (comfortable with Linux environment and web interfaces) ..

 

Preferred qualifications:

  • Degree in biology, structural biology, biophysics, biochemistry, computer science, engineering, or closely related field.
  • Familiarity with biological structures at some level.
  • Ability to contribute to experimental design and assist with the analysis and interpretation of results.
  • Proven organizational and time management skills to successfully set priorities meet established deadlines and recognize new problems.
  • Hands-on experience in maintenance and alignment of electron microscopes.
  • Experience with macromolecular model building in cryoEM density maps.
  • Experience in working in a Linux/UNIX environment and with cluster computing.

 

Application Deadline: 2025-04-24

 

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