• Full Time (Salaried)
  • ,

Company:  Confidential

Job Title: Sr. Scientist

Job Number: 34644

Location:

Job Description

Working within a gene therapy research team, the Senior Scientist will contribute to the discovery and development of AAV-based gene therapies for metabolic diseases. Responsibilities include designing, screening, and characterizing genetic constructs, developing disease models and bioanalytical assays, and collaborating with internal teams and external partners to achieve program goals effectively.

Responsibilities

  • Contribute to characterizing a lead gene therapy program for clinical advancement.
  • Lead development of new gene therapy programs.
  • Design and optimize genetic constructs for effectiveness.
  • Conduct screening for construct specificity and efficacy.
  • Develop and execute molecular assays.
  • Assist in generating data from studies.
  • Prepare technical reports and analyses.
  • Maintain electronic lab notebooks.
  • Stay updated with new technologies.
  • Mentor junior scientists.
  • Ensure compliance with regulations and policies.
  • Adapt to additional responsibilities.

Required Skills

  • Education/Certification: PhD in Biology, Biomedical Engineering, or related fields.
  • Work Experience: 3-5+ years post-PhD in academic or industry settings, preferably in biotech, pharmaceuticals, or medical devices. Prior vocational experience such as internships or fellowships is advantageous. Management/mentorship experience is a plus.
  • Skills: Extensive experience in mammalian cell culture, DNA transfection, and viral transduction (preferably AAV). Proficient in DNA construct design using software, with expertise in molecular assays, molecular biology techniques, and metabolic diseases preferred. Willingness to work with animal models.
  • Key Attributes: Hands-on expertise, ability to lead fast-paced projects, organized with attention to detail, self-motivated team player, excellent communication skills, innovation mindset, professionalism, and ethical standards.
  • Travel: Minimal (<5%) travel may be required for conferences and collaborations.

 

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