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Job Title: Sr. Research Associate – Stability

Job Number: 25619

Location: Lexington, MA

Job Description

We are seeking a highly motivated and scientifically rigorous individual to join the Delivery and Formulation Development team as a Sr. Research Associate. The position will focus on the stability evaluation of frozen and lyophilized drug products.


  • Conduct experiments for advancing the understanding of stability of lipid nanoparticles (LNP) drug products and provide storage and shipping conditions aligned with successful administration of drug product for preclinical and clinical studies.
  • Perform experiments to establish stability parameters, improving physical and chemical stability and integrity of drug product upon long term storage.
  • Support drafting new and revising existing stability protocols for long term stability of drug product.
  • Contribute to writing/reviewing analytical method protocols/stability protocols.
  • Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.

Required Skills

  • B.S./M.S. in Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry.    
  • 4 – 6 years of relevant experience in making lipid nanoparticle (LNP) formulations, analyzing and characterizing LNPs, and working in research/manufacturing/production group.
  • Direct experience with messenger RNA encapsulation/quantification/characterization/handling is preferred.
  • Prior experience working with lyophilized drug products would be preferred.
  • Experience with biophysical characterization assays for lipid delivery systems is required.
  • Experience with screening various LNP stabilizing buffers would be desired.
  • Works collaboratively within group as well as within interdisciplinary teams.
  • Manages time effectively demonstrating ability to perform multiple projects at one time.
  • Desire to work in a fast-paced environment.
  • Excellent organizational and communication skills. 
  • Strong analytical and problem-solving skills.

Translate Bio is committed to equal employment opportunity. All applicants must have authorization to work in the U.S.


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