1-617-500-6690 [email protected]

Korro Bio

Job Title: Sr. Research Associate, Compound Management

Job Number: 31590

Location: Cambridge, MA

Job Description

Korro Bio is seeking a passionate, driven, and creative entry-level scientist/Engineer to join our oligonucleotide discovery chemistry team and work with an enthusiastic team of highly skilled scientists in a dynamic, growing company. The successful candidate will be responsible for handling, characterization, automation, storage and distribution of oligonucleotide compounds and work closely with cross functional team to advance our RNA editing drug discovery programs. The candidate will also be responsible for quantifying, performing purity analysis via HPLC/LCMS, and documenting results. Additional responsibilities include working with the group to maintain an organized physical and virtual lab to meet the needs of our fast-growing organization. Candidate must express a high attention to detail, be comfortable multitasking and ability to function in an interdisciplinary and fast-paced startup environment.

Responsibilities

  • Oligonucleotide compound management and preparation of samples for biological screening
  • Analysis and formulation of test articles for in vitro and in vivo studies
  • Receive, track, and maintain physical and virtual inventory of compounds
  • Quantification of oligonucleotide compounds via UV spectrophotometry
  • Perform duplex & triplex of oligonucleotides and run melting studies
  • Purity analysis via analytical HPLC and LCMS
  • Documentation, report generation and presentation of results
  • Maintain a well-documented electronic/laboratory notebook

Required Skills

  • Bachelor’s degree with 1-3 years of experience in an industrial or academic laboratory setting
  • Experience with nucleic acids and analytical chemistry is a plus
  • Experience with lab automation a plus
  • Experience with LIMS systems and order tracking
  • High attention to detail with the ability to handle large sets of compounds accurately
  • Experience with UV spectrophotometry, HPLC, and LCMS analysis
  • Good laboratory hygiene and extraordinary organizational skills
  • High degree of flexibility and self-motivation in a fast-paced work environment, ability to prioritize appropriately and meet deadlines
  • Excellent interpersonal, communication and presentation skills

 

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