Company:  Confidential

Job Title: Senior Staff Scientist (87647BR)

Job Number: 76811

Location: New Haven, Connecticut, US

Job Description

[Please click the Apply button for the link or email] at Yale School of Medicine is seeking a talented, skilled, and highly motivated researcher to assume the role of [Please click the Apply button for the link or email] to lead and perform the FIB-SEM sample preparation and image acquisition operations. At the forefront of volume Electron Microscopy, the F-SCC utilizes the state of the art enhanced Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for large volume imaging with nanometer isotropic resolution. Under supervision of the Director, the candidate will be responsible for pipeline processes of X-ray guided FIB-SEM sample preparation, enhanced FIB-SEM image acquisition, and image registration and alignment. The candidate is expected to be multi-tasking, perform independent experiments using the state-of-the-art laboratory techniques including enhanced Focused Ion Beam Scanning Electron Microscopy and X-ray micro-CT. The candidate will work closely with supervisor, group members, and collaborators.

While the job duty will evolve according to the needs of the organization, specific responsibilities include: 1) Perform FIB-SEM sample preparation: mount and trim heavy metal-stained and resin-embedded samples to target specific region of interest using an ultramicrotome guided by X-ray micro-CT. 2) Perform FIB-SEM image acquisition using customized enhanced FIB-SEM microscopes. Optimize imaging conditions for the best results. Maintain equipment and troubleshoot hardware and software related issues. Perform system installations and upgrades when needed. 3) Perform 3D image registration and alignment. 4) Perform IT related system administration duties to maintain image analysis and data storage platform.

Preferred Education, Experience and Skills: Ph.D. degree in experimental physics, physical chemistry, engineering, material science or other related discipline, plus five years of relevant experience. Special considerations will be given to those who have expertise in LabVIEW, Python, and MATLAB. Experience in database management (MySQL) and virtual machine environments (VMware ESXi) is a plus.

Application Deadline: 2024-09-02


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