Senior Scientist, Statistical Genetics

Job Title: Senior Scientist, Statistical Genetics

Job Number: 34895

Location: South San Francisco, CA

Job Description

Responsibilities

• Work in close collaboration with data science and functional genomics to integrate results from functional genomics studies with human genetics data for new target identification/prioritization
• Leverage major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms, breakthrough understanding of biological pathways, functional genomics capabilities
• Identify and integrate data tools to expand analysis capabilities and maintain and up-to-date understanding of statistical genetics capabilities
• Perform and interpret human genetic analyses using public and internal data to identify new targets and therapeutic hypotheses
• Contribute to writing patents, reports and scientific publications

Required Skills

• Ph.D., M.D. or M.D.-Ph.D. with significant relevant experience in genetics/bioinformatics/computational biology and the biologic interpretation of human genetic data
• Well versed in the management and analysis of large datasets, including those derived from SNP arrays and next-generation sequencing platforms
• In depth knowledge with GWAS
• Experience in the analysis of large-scale genomic association studies in complex genetic diseases including correcting for population stratification and imputation of genotypes.
• A strong computational/statistical background (perl, python, R or others) is highly desirable
• Experience with Mendelian Randomization (or other causality inference approaches) or analysis of crispr screens is a plus
• Communication skills to clearly present data and your interpretation of the results
• A highly motivated disposition and desire to push new scientific boundaries