Tango Therapeutics

Job Title: Senior Scientist, Immunology

Job Number: 19247

Location: Cambridge, MA

Job Description

We are seeking an innovative, collaborative and enthusiastic immunologist to work on building our Immunology and Immuno-Oncology Programs. This individual will focus on bench science for projects centered on target identification, validation, and patient selection strategies.


  • Experimental strategy and design for the study of anti-tumor immune responses using in vitro systems and syngeneic murine models
  • Production, culture, maintenance, and genetic perturbation of human and murine tumor cell lines
  • Use of transfection or transduction to generate novel cellular reagents
  • Isolation, culture, and genetic perturbation of immune cell subsets (primarily T cells) from both mouse and human
  • Assessment and analysis of immune cell phenotype and function by multicolor flow cytometry, ELISA, and gene expression analysis
  • Assist with the training of lab personnel
  • Analysis and presentation of results to larger scientific groups
  • Work productively in a team environment and independently and deliver against timelines

Required Skills

  • Ph.D. in Immunology with 0-8 years of experience in industry
  • Postdoctoral experience is preferred
  • An understanding of adaptive immunity in the context of cancer
  • Experience with flow cytometry and related data analysis
  • Experience with functional immune assay development, including cytokine assays
  • General molecular biology experience is strongly preferred
  • General computational biology experience is strongly preferred
  • Experience with lentivirus preparation and infection is strongly preferred
  • Ability to organize, analyze and present data
  • Excellent record-keeping skills
  • Strong written and oral communication skills
  • Independent and self-motivated


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