1-617-500-6690 [email protected]
  • Full Time (Salaried)
  • Boston, MA

Stealth NewCo Gene Editing & Delivery

Job Title: Senior Research Associate – Molecular Technologies

Job Number: 30853

Location: Boston, MA

Job Description

Sci.bio has partnered with an exceptionally well funded, gene-therapy stealth co aiming to unlock the full potential of gene therapy based on
a novel delivery platform coupled with proprietary CRISPR gene editing technology . This is not your average start-up and is founded by a prominent, world-class leadership team and Board of Directors.

 What makes us different? Over the last decade significant progress has been made in developing powerful technologies for genomic medicines. However, one major challenge for gene therapies remains: the effective and safe delivery of genetic information to patients. Our modular gene delivery platform, derived from the human genome, allows us to package and deliver therapeutic payloads safely into the human body. Together with compact CRISPR gene editors, our approach positions us to overcome these challenges and transform the way genomic medicines are developed and deployed.  

 We are founded by a world leader in CRISPR technologies, with a best in class Board of Directors, and funded by investors committed to our mission.  

 We are seeking energetic, motivated scientists to join our team in developing these new technologies and who are unwavering in their commitment to making an impact on patients’ lives. As an early member, you will help shape our scientific foundation and company culture.

Overview

We are seeking an independent, highly motivated, and skilled bench-based Senior Research Associate with a background in molecular and cell biology. In this role, you will perform various experiments in mammalian tissue culture, molecular cloning, and NGS library preparation.  A successful candidate will perform experiments independently but with ample support from our growing team and will be excited by a start-up environment.

Responsibilities

  • Perform experiments for the maintenance and care of mammalian cell cultures including routine feeding, passaging, and harvesting of cells, independently. 

  • Perform mammalian cell transfections and nucleic acid extractions. 

  • Independently perform experiments for production of recombinant DNA including bacterial transformation, purification of DNA plasmids, PCR, sequence verification, etc. 

  • Prepare and QC nucleic acid libraries for Next Generation Sequencing. 

  • Record experimental data and analysis in an electronic laboratory notebook.

  • Actively participate in discussions about data and research directions with the team. 

Required Skills

  • Bachelor’s degree in Molecular Biology, Cell Biology, Biochemistry, or related field with >3 years of experience, or Master’s Degree with >1 year of experience (industry preferred).

  • Hands-on experience with molecular cloning and recombinant DNA preparation.

  • Proficiency in mammalian tissue culture methodologies. 

  • Experience in NGS library preparation. 

  • Direct hands-on experience and deep knowledge of CRISPR-Cas systems is a plus. 

  • Strong organizational skills, attention to detail, and a commitment to keep accurate, detailed experimental records with scientific integrity. 

  • Independence with routine laboratory work but scientific curiosity and a willingness to ask questions or learn new research methods. 

  • Interest and flexibility in working for a growing organization. IND-1

 

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