1-617-500-6690 [email protected]

Goldfinch Bio

Job Title: Senior/Principal Scientist, Biology

Job Number: 28676

Location: Cambridge, MA 02142

Job Description

We’re seeking a highly motivated Senior Scientist or Principal Scientist with a strong background in renal biology to join our Biology Department and contribute to building our pipeline for renal diseases. The successful candidate will focus on driving scientific research to establish and validate novel targets for kidney disease. Responsibilities include leading and mentoring a team of scientists, development, characterization and implementation of models of kidney disease based on human biology, and implementing models for evaluation of potential therapeutics.


  • Collaborate with scientists in cross-functional teams to discover tractable, high-impact disease targets.
  • Develop strategy and scientific approach to establish and characterize novel targets for kidney disease.
  • Establish in vitro assays to evaluate dose/response relationships, efficacy, and characterize molecules for potential therapeutic effects.
  • Initiate and manage external research collaborations to further the applications of in vitro models of chronic kidney disease.
  • Lead a group of researchers within Biology, providing guidance and mentorship.
  • Prepare, review and deliver high quality scientific presentations for internal/external use.
  • Commit to helping the team achieve deliverables and meet aggressive timelines.

Required Skills

  • PhD with at least 5 years post-degree research in the kidney disease field, translational experience is an asset. Prior work industry experience is an advantage but is not required.
  • Extensive hands-on experience with cell culture, in vitro and/or in vivo models of kidney disease.
  • Hands-on experience in cellular and biochemical techniques including standard molecular biology and protein biochemistry methods and proven assay troubleshooting skills.
  • Hands on experience in the development and validation of cell-based assays.
  • Experience with iPSCs and organoids is desirable.
  • Strong publication record and demonstrated experience conducting independent research.
  • Strong leadership and evidence of strategic scientific thinking.
  • Effective managerial skills and prior experience mentoring junior scientists with different skill sets.


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