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Job Title: Senior Associate Scientist Production, Purification (CMC)

Job Number: 31116

Location: Cambridge, MA, 

Job Description

The CMC Team in Cambridge is seeking a Senior Research Associate. The candidate will work in the EV Production Center under the VP of CMC's direction to create high-quality RBCEVs that form the foundation of our Research and Development efforts. The candidate will work closely with the Discovery, Biology, and Downstream Purification groups to align RBCEV needs and optimal purification strategies for RBCEV generation.


  • Coordinate RBCEV material needs across Carmine functions with the assistance of the VP of CMC, and purify RBCEVs using existing protocols for use in studies across the Company
  • Train incoming group members on current RBCEV purification processes
  • Assist in maintaining external CMO relationships with commercial partners should external support be needed based on demands
  • Collaborate with cross-functional teams
  • Participate in presentations, reports, patent filings, and external communications
  • Support the continued creation and expansion of company’s intellectual property

Required Skills

  • A purification scientist with a B.S. or M.S. in bioengineering or a related scientific discipline and 1-5 years of experience in purification in an industry setting, with novel modality experience preferred
  • A quality-focused approach to both purification and documentation is essential; as such, prior experience in a Manufacturing or Quality Control setting is an advantage
  • Experience in the following would be an asset: AKTA purification, UF/DF, or TFF
  • Knowledge of gene therapy/nucleic acid delivery/extracellular vesicles is an advantage
  • Team oriented, highly motivated, execution-focused with a strong work ethic, and the ability to thrive in an entrepreneurial and multidisciplinary environment


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