1-617-500-6690 [email protected]

Carmine Therapeutics

Job Title: Senior Associate Scientist Process Development, Purification (CMC)

Job Number: 31112

Location: Cambridge, MA

Job Description

The CMC Team in Cambridge is looking for a Senior Research Associate to work under the direction of the Process Development team to develop and implement purification schemes for RBCEVs. Reporting to the Head of Process Development, this position will assist in creating phase-appropriate purification processes for RBCEV development candidates.


  • Execute experimental plans in coordination with development objectives of the CMC team, which are initially to develop scalable purification processes for loaded and unloaded RBCEVs 
  • Stay abreast of the latest scientific and competitive developments for EV purification and apply this knowledge to both team strategy and incoming development candidates
  • Assist in presentations, reports, patent filings and external communications as required
  • Assist in maintaining and managing external CMO relationships with commercial partners
  • Collaborate with cross-functional teams
  • Participate in presentations, reports, patent filings, and external communications
  • Support the continued creation and expansion of company’s intellectual property

Required Skills

  • A purification scientist with a B.S. or M.S. in bioengineering or a related scientific discipline and 2-5 years of experience in purification in an industry setting, with novel modality experience preferred
  • Experience in the following would be an asset: AKTA purification of multiple biological modalities, UF/DF or TFF experience with larger biological modalities (e.g. viruses), and tech transfer of developed processes to a manufacturing setting
  • Knowledge of gene therapy/nucleic acid delivery/extracellular vesicles is an advantage
  • Team oriented, highly motivated, execution focused with strong work ethic, ability to thrive in an entrepreneurial and multidisciplinary environment


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