1-617-500-6690 [email protected]
  • Full Time (Salaried)
  • Boston, MA

Stealth NewCo Gene Editing & Delivery

Job Title: Scientist/Senior Scientist Gene Editing Transposable Elements

Job Number: 31151

Location: Boston, MA

Job Description

Reporting to the Head of Molecular Technologies, the Scientist/Senior Scientist Transposable Elements will contribute to a fast paced and innovative team of scientists and research associates focused on developing novel gene editing and delivery technologies. The goal of the Molecular Technologies team is to engineer these technologies at the mechanistic level, and to advance the cutting edge of delivery and gene editing systems. The individual in this role will leverage their deep expertise and knowledge of mobile genetic element structure and function to engineer transposable elements and their associated proteins. The ideal candidate will have a track record of developing assays and techniques for interrogating mobile genetic elements functionally, and an interest in translating your expertise into genome therapies.

Responsibilities

● Design and implement molecular, biochemical and biophysical assays to measure and engineer the activities of transposable elements. 

● Produce and optimize reagents for both delivery and gene editing experiments. 

● Work collaboratively with computational and delivery teams to design and discover transposable elements for biotechnology. 

● Innovate and establish high throughput workflows with the discovery platform. 

● Manage external collaborations and screening campaigns. 

● Help drive emerging gene editing and delivery technologies towards human therapeutics. 

● Collaborate across various research teams within the company, communicate plans and discoveries, and help to foster thoughtful and productive scientific dialogue. 

● Document scientific progress with rigor, thoroughness, precision and an eye towards collaboration. 

Required Skills

● PhD in molecular biology, structural biology, biochemistry, molecular virology or cell biology, or similar with at least 3+ years’ hands-on research experience.. 

● Strong candidates with Bachelors (8-10 years) or Masters (6-8 years) in related disciplines will also be considered. 

● A scientist with computational skills related to transposable element identification is desirable but not a requirement 

● A proven track record of expertise in transposable element biochemistry, molecular biology, structural biology, computation or a related discipline. 

● Experience with enzymes and proteins involved in DNA/RNA metabolism is a major plus. For example, DNA recombination and DNA repair. 

● Hands on experience and expertise in molecular cloning, measuring , qPCR and/or ddPCR. Genetic copy number variation(CNV), long read DNA sequencing, 

● Prior experience in gene editing technologies is not required but highly desirable. 

● Self-motivated, organized, and excellent communication skills.

Our stealth company is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics. Valuing respect, curiosity and inclusivity is required. 

 

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