Casebia Therapeutics

Job Title: Scientist, Ophthalmology

Job Number: 21043

Location: Cambridge, MA

Job Description

We are seeking a highly motivated scientist, who is keen to develop novel gene editing therapies in Ophthalmology. Applicants should have deep knowledge and hands-on experience in the use of gene editing tools, preferably CRISPR/Cas9 as well as viral (e.g. AAV, Lentiviral) delivery of these tools. The successful candidate must be capable of identifying new areas of research, prioritizing existing projects, and contributing to Casebia’s strategic research plans. Familiarity with various inherited ophthalmic disorders and experience with managing projects and research teams are preferred.


  • Design and perform research independently to advance on-going/new preclinical programs from discovery to IND/CTA.
  • Collaborate with and mentor Research Associates
  • Record experimental results precisely and timely.
  • Leverage external research collaborators
  • Investigate, create, and/or develop new methods and technologies
  • Assist in securing intellectual property, including detailed descriptions for patent filing and/or proof of concept work
  • Present scientific data in internal and external meetings.

Required Skills

  • PhD in molecular biology, cellular biology or related field with a total of 5+ years experience including 0-3 years’ industry experience.
  • Hands-on experience with a range of molecular biology and cell-based assays.
  • Proven track record of publications and/or patents in DNA repair, genome editing, gene therapy, and/or viral delivery.
  • Excellent oral and written communication skills
  • Ability to work in a team-oriented environment but also be a self-starter, internally motivated, with the ability to work independently to drive the research forward
  • Scientifically rigorous, highly organized, with significant attention to detail.
  • Knowledge of the pathophysiology and treatment of ophthalmic disorders and related genetics is desirable, but not essential.
  • High energy level, focus, a passion and sense of urgency for developing important new medicines for devastating diseases


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