Scientist, Next Generation Sequencing

Job Title: Scientist, Next Generation Sequencing

Job Number: 32347

Location: , 

Job Description

Responsibilities

Responsibilities: 

• Contribute to the development of NGS assays to benefit drug discovery and translational research

• Generate NGS libraries and perform library QC upstream of sequencing

• Develop and edit protocols and standard operating procedures

• Support department and corporate goals in NGS.

• Carry out NGS and epigenomics assays to support large collaborative initiatives

• Effectively communicate results in a group setting

• Maintain an accurate and complete laboratory notebook and other records, as needed

• Assist with lab organization and compliance with lab safety protocols

• Coordinate with the Bioinformatics group, internally and externally, to process sequence data 

Required Skills

Qualifications:

• Ph.D.or MS degree with 3 more years of professional experience in molecular biology, biotechnology, or cell biology

• Demonstrated expertise in molecular biology techniques, including DNA/RNA extraction & purification, NGS library preparation & QC, PCR, qPCR, etc.

• Hands-on experience with single-cell sequencing assays 

• Demonstrated experience in nucleic acid extraction from tissues as well as plasma and cells for NGS applications

• Strong understanding of NGS technologies, with a track record of utilizing such assays in a research environment; A deep understanding of molecular biology and biochemical techniques relevant to assay development.

• Familiarity with Illumina sequencing, and hands-on experience in the generation and QC of Illumina sequencing libraries

• Experience with standard molecular biology tools e.g., PCR, qPCR, gel and capillary electrophoresis

• Being Familiar with R/Pythonis a big plus

• Strong analytical and troubleshooting skills demonstrated through examples of projects supported

• Ability to use technical skills and good time management to perform work efficiently and meet project timelines

• Excellent verbal and written communication skills with a particular emphasis on clear documentation of experiments and studies are essential, as is a willingness to collaborate cross-functionally in a fast-paced and dynamic environment.