Job Title: Research Associate/Sr. Research Associate, Formulations
Job Number: 23041
Location: Lexington, MA 02421
We are seeking a highly motivated and scientifically rigorous individual to join the Research and Process Development team as a Research Associate / Senior Research Associate. The position will report to the Director of the group and will focus on developing novel lipid nanoparticle (LNP) formulations for mRNA delivery.
- Provide formulations and perform characterization assays /data analysis with focus on in vivo studies, drug carrier design/development, assay development etc.
- Support formulation development activities related to formulation optimization with focus on potency and tolerability.
- Develop novel formulations for different ROAs.
- Contribute in writing/reviewing analytical method protocols & stability protocols.
- Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.
- B.S./M.S. in Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry
- 0 – 4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization
- Direct experience with messenger RNA encapsulation/quantification/characterization/handling is preferred
- Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred
- Understanding and success in implementation of RNA-related analytics (Ribogreen, gel electrophoresis, capillary electrophoresis, etc.) is desired.
- Experience in developing lyophilized formulations would be advantageous
- Works collaboratively within group as well as within interdisciplinary teams
- Manages time effectively demonstrating ability to perform multiple projects at one time
- Desire to work in a fast-paced environment
- Excellent organizational and communication skills
- Strong analytical and problem-solving skills
Translate Bio is committed to equal employment opportunity. All applicants must have authorization to work in the U.S.