Cogen Immune Medicine
Job Title: Research Associate, Protein Production and Analytics
Job Number: 23195
Location: Cambridge, MA 02139
Reporting to the Head of Protein Production and Analytics, the Research Associate will play a key role as part of a world-class team exploring novel targets to gain unique insights into our immune system.
The Research Associate will be responsible for contributing to the execution of the Protein Sciences team’s milestones. Responsibilities include, (1) production and characterization of unique antigens and proteins that will enable new understandings of immune cell biology and support therapeutic discovery (2) and working closely with early Technology development, Protein Sciences, Immunology and Molecular Biology to support the ongoing evolution of the platform.
The Research Associate's key scientific mission will be to execute and optimize protein production and characterization to support Cogen Immune Medicine’s premier protein platform that serves as the functional core for empowering a robust therapeutic pipeline.
The successful candidate should have a B.S. or M.S. in Biochemistry, Chemistry, Chemical Engineering or a related discipline with 0-2 years of industry experience. A basic understanding of molecular biology, protein biochemistry, and common protein expression and purification techniques is required. The candidate will be well-organized and proactive. Hands-on experience in purification strategies, mammalian and bacterial expression, and analytical equipment would be beneficial.
Experience in the following areas is highly desirable:
- Mammalian cell culture and transient transfections
- E. coli expression, inclusion body purification and protein refolding.
- Protein purification (affinity, IEX, SEC).
- Automated purification instrumentation (ÄKTA or similar).
- Protein characterization, including SDS-PAGE, Western blot, ELISAs
- Protein analytical and biophysical methods, including HPLC.
- Documentation in electronic lab notebook and bioregistration systems.
The Research Associate will possess excellent interpersonal skills and a successful track record of working in a fast-paced environment. The Research Associate will be responsible, creative, team-oriented, able to learn and execute protocols quickly, and able to and document appropriately. We are looking for an enthusiastic scientist that is easy to work with, adaptable and open to new ideas.
A lucrative overall compensation package including:
Competitive base salary, bonus potential and stock options.