Company:  Confidential

Job Title: Research Associate- Kapahi Lab

Job Number: 72501

Location: Novato, US

Job Description

Join the Kapahi Lab as a Research Associate! Unlock the Secrets of the Hallmarks of Aging!

Are you passionate about unraveling the mysteries of aging and eager to delve into the fascinating world of hallmarks of aging? The Kapahi Lab is looking for a dynamic and driven individual to join our team as a Research Associate. If you have a thirst for knowledge and aspire to contribute to cutting-edge research in a collaborative and progressive environment, we invite you to apply.


In the ever-evolving landscape of modern diet and lifestyle, a concerning trend has emerged – the association between these factors and health issues such as obesity and insulin resistance. These conditions, in turn, contribute to the onset of age-associated disorders, including Alzheimer’s disease. The intricate link between insulin resistance and the neurodegenerative process has been established through various studies. Despite recognizing this correlation, the development of molecular therapies faces significant challenges. The elusive nature of the endogenous drivers behind this pathology has hindered progress in finding effective treatments. At the Kapahi Lab, we are addressing this gap by employing cutting-edge drug screening methodologies.

Our research focuses on screening metabolites using state-of-the-art techniques. By identifying compounds that reduce obesity and enhance insulin sensitivity, we aim to unravel the molecular mechanisms at play. This approach holds promise in not only addressing insulin resistance but also in potentially improving the neurodegenerative aspects associated with conditions like Alzheimer’s disease. Our investigations utilize both mouse models and cell culture methods, allowing us to explore and understand the complex interactions at a molecular level. Through this innovative approach, we strive to pave the way for novel therapeutic interventions in the realm of age-associated disorders.


·         Aging Research Focus: Become an integral part of a team dedicated to advancing our understanding of aging processes.

·         Emphasis on Learning and Progress: Join a culture that prioritizes continuous learning and professional development. We believe in fostering an environment where your curiosity is encouraged, and your potential is nurtured.


·         Tissue Histology: Proficiency in both paraffin and cryo histology techniques is required.

·         Mice Handling and Breeding Facility: Demonstrate expertise in the responsible and ethical care of research mice, including breeding protocols.

·         Western Blotting: Execute western blotting techniques with precision and accuracy.

·         Real-Time PCR: Conduct real-time PCR experiments and analyze results.


·         BA/BS in Biology or related field

·         Passion for Aging Research: If you have a genuine interest in aging biology, this is the place for you.

·         Team Player: Thrive in a collaborative team environment that values collective progress.

·         Research Experience: Prior experience in western blotting and real-time PCR is highly desirable.

·         Analytical Skills: Demonstrate strong analytical and problem-solving skills.

·         Adaptability: Ability to adapt to evolving research priorities and techniques.


Salary: $50,000 – $67,000 commensurate with lab/research experience.
This is a full-time, onsite position.
Generous benefits package including health insurance, paid parental leave, childcare assistance, generous holiday/vacation/sick leave, and 401(k) with 5% employer match.

Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede how we age. We are an independent, non-profit institution located in Marin County, CA, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging number one risk factor for diseases including Alzheimer’s, Parkinson’s, cancer, macular degeneration, heart disease, and diabetes. Buck seeks to help people live better longer. We are an equal-opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.


Be a catalyst for progress and contribute to groundbreaking research in the field of aging. If you’re ready to embark on a rewarding journey of discovery, learning, and scientific advancement, apply now and be part of a team where your skills and passion truly make a difference!

Please apply online; upload a CV and cover letter including contact information for 3 professional references.

Application Deadline: 2024-03-31


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