Principal/Senior/Scientist, Bioorganic Chemistry

Job Title: Principal/Senior/Scientist, Bioorganic Chemistry

Job Number: 84856

Location: Cambridge, US

Job Description

We are looking for a highly skilled Synthetic Bioorganic Chemist with hands-on experience in nucleoside/nucleotide and heterocyclic chemistry. The ideal candidate will have a strong background in organic synthesis, with a particular emphasis on bioorganic applications. Experience in oligonucleotide synthesis is highly desirable. This role involves designing and executing complex synthetic routes, optimizing reaction conditions, and analyzing and characterizing chemical compounds to support our research and development efforts.

Responsibilities

* Design and synthesize nucleosides, nucleotides, and heterocyclic compounds for various research projects. * Develop and optimize synthetic routes and methodologies for bioorganic applications. * Perform oligonucleotide synthesis and modify oligonucleotide sequences as needed. * Analyze and characterize compounds using techniques such as NMR, MS, HPLC, and other analytical methods. * Troubleshoot and resolve synthetic challenges, ensuring high purity and yield of target compounds. * Collaborate with interdisciplinary teams to integrate synthetic chemistry efforts with broader research objectives. * Document experimental procedures, results, and interpretations in a clear and organized manner. * Stay up to date with advancements in synthetic chemistry and bioorganic research, incorporating new techniques and methodologies as appropriate. * Adhere to safety protocols and best practices in the laboratory.

Required Skills

* Ph.D. in Organic Chemistry, Bioorganic Chemistry, or a related field, with a focus on synthetic chemistry. * Scientist I/II (0-3), Senior Scientist (4-6), Principal (+6) years of experience * Proven hands-on experience with nucleoside/nucleotide chemistry and heterocyclic chemistry. * Demonstrated experience in oligonucleotide synthesis is a strong plus. * Proficiency in modern analytical techniques (e.g., NMR, MS, HPLC) and interpretation of data. * Excellent problem-solving skills and the ability to work independently as well as part of a team. * Strong communication skills, with the ability to present complex information clearly and effectively. * A track record of publication or presentation in relevant scientific areas is desirable.Join the mission to develop innovative therapies and make a meaningful impact on patients’ lives. They offer competitive compensation, comprehensive benefits, and opportunities for professional growth and development. If you are looking for a new challenge and the opportunity to contribute to cutting-edge science, please apply!

Application Deadline: 2024-11-04