Company:  Confidential

Job Title: Postdoctoral researcher

Job Number: 57015

Location: Chicago, US

Job Description

Dr. Caner Saygin`s laboratory at the University of Chicago Comprehensive Cancer Center is seeking a highly motivated and talented post-doctoral researcher to join our team. Our lab focuses on the investigation of leukemia evolution from pre-leukemic states (e.g., clonal hematopoiesis) and development of novel experimental therapeutics for treatment of acute leukemia. This position presents a unique opportunity to contribute to groundbreaking research aimed at improving therapeutic approaches and patient outcomes in acute leukemia.

Position: Post-Doctoral Researcher Lab: Caner Saygin’s Lab Research Focus: Biology and Treatment of Acute Leukemias


Conduct cutting-edge research on the molecular mechanisms of leukemogenesis, including single cell multi-omics (RNA-seq, proteomics, DNA seq) analysis of primary human samples and transgenic animal models with clonal hematopoiesis and acute leukemia (AML and ALL).

Study the mechanisms driving lymphoid vs myeloid leukemogenesis from clonal hematopoiesis (in vivo models and patient samples).

Design and execute experiments utilizing cell lines, patient-derived samples, and animal models to evaluate novel therapeutic strategies.

Investigate mechanisms of treatment resistance in acute leukemia, including resistance to chemotherapy and targeted therapies.

Collaborate with multidisciplinary teams within the lab and establish collaborations with external research groups.

Analyze and interpret experimental data, prepare scientific reports, and present findings at national and international conferences.

Publish research findings in scientific journals to contribute to the scientific community’s understanding of clonal hematopoiesis and acute leukemia.


Ph.D. in a relevant field (e.g., Molecular Biology, Cancer Biology, Hematology) or M.D. with sufficient laboratory research experience

Strong background in cancer biology, genetics, molecular signaling pathways, and/or hematological malignancies.

Experience in cell culture techniques, molecular biology techniques (PCR, cloning, Western blotting, etc.), and functional assays.

Proficiency in bioinformatics and data analysis tools for high-throughput genomic data would be advantageous.

Demonstrated ability to work independently, design and execute experiments, and troubleshoot technical challenges.

Excellent verbal and written communication skills, with the ability to present research findings effectively.

Strong publication record or evidence of potential to publish in peer-reviewed scientific journals.

We offer:

An exciting and innovative research environment at the forefront of cancer biology research.

Access to state-of-the-art facilities, cutting-edge technologies, and a diverse range of scientific expertise.

Collaborative and supportive mentorship from Dr. Caner Saygin, an experienced physician scientist dedicated to the professional growth and development of the post-doctoral researcher.

Additional mentorship provided by Dr. Wendy Stock, who will provide guidance and support in research and career development.

Competitive salary and benefits package commensurate with qualifications and experience.

Opportunities for career advancement, including potential for transitioning to independent research positions or pursuing academic faculty positions.

Application Process:

Interested candidates are invited to submit their application electronically, including the following documents:

·         Cover letter outlining their research interests, relevant experience, and motivation for joining our lab.

·         Curriculum Vitae (CV) with a list of publications.

·         Contact information for three professional references.

Applications will be reviewed on a rolling basis until the position is filled.

Dr. Saygin and the lab team are committed to promoting diversity and inclusion in research. We encourage applications from individuals of all backgrounds and experiences. University of Chicago can sponsor visas for qualified international candidates.

Join our lab and contribute to advancing our understanding of acute leukemia! Together, we can make a difference in the lives of patients battling this devastating disease.

Application Deadline: 2023-12-05


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