Company:  Confidential

Job Title: Postdoctoral Research Associate

Job Number: 72085

Location: Philadelphia, US

Job Description

Postdoctoral Research Associate in Leukemia Evolution 

Robert Bowman Lab – University of Pennsylvania

Position Overview:

The Bowman Lab at the University of Pennsylvania is seeking a Postdoctoral Research Associate to join our research team. Our lab focuses on investigating the mechanisms underlying evolution of hematopoietic stem and progenitor cells to acute myeloid leukemia (AML). The successful candidate will have the opportunity to contribute to cutting-edge research in cancer biology, working closely with a collaborative team of scientists and clinicians.

Lab Description:

The Bowman Lab is dedicated to unraveling the complexities of AML through a multidisciplinary approach.  Special topics of Interest include: 1) understanding how mutation order influences leukemic cell of origin, 2) evaluating therapeutic strategies for targeting leukemic stem cells, and 3) dissecting leukemic clone crosstalk in disease development. Through this work we aim to identify means to revert or halt leukemic transformation early in disease development.  To achieve these goals, we use a combination of multi-recombinase genetically engineered mouse models and single cell genomics.  For more information about our ongoing projects and scientific approach, please visit our website: [Please click the Apply button for the link or email]


Minimum salary for this position is $65,000. 

What we offer:

We are committed to providing a rich environment for you to develop your scientific skillset, contribute meaningfully to the field and build your scientific professional network. We have a successful track record in training biologists in computational methods and in training dry-lab focused researchers in biological methods for evaluating hypotheses of interest. We are wholly committed to helping you develop these skills and prepare you for the next stage of your career.


As a Postdoctoral Research Associate in the Bowman Lab, you will be at the forefront of investigating the molecular intricacies of Acute Myeloid Leukemia (AML). Your responsibilities will include:

1. Independent Research:
Design, plan, and execute independent research projects within the overarching goals of the lab.
Utilize advanced molecular biology techniques, genomics, and functional genomics approaches to unravel key aspects of AML biology.
2. Collaborative Teamwork:
Collaborate effectively with other lab members, contributing your expertise to multidisciplinary research endeavors.
Engage in regular research group meetings, fostering a collaborative environment to share insights and feedback.
3. Experimentation and Optimization:
Perform laboratory experiments, troubleshoot technical challenges, and optimize protocols to ensure the reliability and reproducibility of results.
Contribute to the development and implementation of new experimental techniques.
4. Manuscript Preparation and Publication:
Prepare manuscripts for publication in peer-reviewed scientific journals.
Contribute to grant writing and assist in securing external funding for ongoing and future projects.
5. Scientific Presentations:
Present research findings at national and international conferences.
Engage with the scientific community through seminars, workshops, and networking events.
6. Training and Mentorship:
Supervise and mentor junior lab members, including graduate students and research assistants.
Foster a positive and collaborative learning environment within the lab.
7. Professional Development:
Stay up to date with the latest advancements in AML research through literature review and attendance at relevant scientific meetings.
Pursue opportunities for professional development, including workshops and courses.


The successful candidate for the Postdoctoral Research Associate position in the Bowman Lab should possess a diverse set of qualifications that align with our research goals. This can come from many different research backgrounds. Qualifications include:

1. Educational Background:
Ph.D. in a relevant field, such as Cancer Biology, Molecular Biology, Genetics, or a related discipline.
Strong academic record and evidence of research productivity.
2. Research Expertise:
Substantial experience in cancer research, with a specific emphasis on leukemia highly desirable.
Proficiency in experimental design, execution, and data analysis related to genomics, molecular biology, and functional genomics techniques.
3. Technical Skills:
Hands-on experience with advanced molecular biology techniques, including but not limited to CRISPR/Cas9, next-generation sequencing, and gene expression analysis.
Competence in cell culture techniques and functional assays related to cancer biology.
Prior experience with mouse models would be highly valuable.
4. Communication Skills:
Excellent verbal and written communication skills demonstrated through presentations at scientific conferences and publications.
Ability to work collaboratively within a team and effectively communicate research findings to a diverse audience.
5. Independence and Initiative:
Ability to work independently, demonstrating initiative and self-motivation in the design and execution of experiments.
Proven capacity to contribute novel ideas and approaches to research projects.
6. Project Management:
Effective project management skills, including the ability to plan and execute experiments within specified timelines.
Experience coordinating multiple aspects of research projects and collaborating with diverse teams.

The Bowman Lab values diversity and encourages applications from individuals of all backgrounds. Join us in advancing the understanding of AML and making impactful contributions to leukemia research.


Interested candidates should submit the following materials-

Cover letter describing research interests and career goals.

CV with a list of publications.

Contact information for three professional references.

Application Deadline: March 31st, 2024

Anticipated Start Date: May 1st, 2024.

Application Deadline: 2024-03-31


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