Company:  Confidential

Job Title: Postdoctoral Position in Biophysics and Chemical Biology

Job Number: 76841

Location: Boulder, US

Job Description

The Walczak group at the University of Colorado invites applications for a postdoctoral position in biophysics and chemical biology. This position offers an opportunity to engage in research focused on unraveling the biophysical and molecular aspects of protein dysregulation and its pivotal role in neurodegeneration. Our multidisciplinary team is dedicated to discovering mechanisms and therapeutic strategies that can mitigate or reverse the progression of Alzheimer’s disease, leveraging our approaches in [Please click the Apply button for the link or email], [Please click the Apply button for the link or email], and neurobiology.

Key Responsibilities

  • Conduct research on the structure, function, and dysregulation of tau and other proteins in Alzheimer’s disease.
  • Apply biophysical techniques, including but not limited to, cryo-electron microscopy (cryo-EM) and cryoET, nuclear magnetic resonance (NMR) spectroscopy, and single-molecule fluorescence spectroscopy.
  • Utilize chemical biology approaches to identify and characterize small molecules or peptides that modulate tau pathology.
  • Collaborate with a dynamic team of researchers to develop and test novel therapeutic approaches.
  • Publish research findings in high-impact journals and present at international conferences.


  • A Ph.D. in Biology, Biophysics, Biochemistry, Neurobiology, or a related field, completed by the start date.
  • Demonstrated experience in protein biochemistry, structural biology, or related methodologies.
  • Experience in studying molecular and cellular mechanism of neurodegeneration is desirable but not required.
  • Experience with mammalian cell culture is desirable but not required.
  • Strong publication record in peer-reviewed journals.
  • Excellent written and verbal communication skills.
  • Ability to work collaboratively in a multidisciplinary research environment.


  • Competitive salary commensurate with experience and qualifications.
  • Access to state-of-the-art facilities and resources.
  • Comprehensive health insurance.
  • Opportunities for professional development and networking.
  • Support for conference attendance and research dissemination.

Application Process

To apply, please submit the following:

· A cover letter explaining your interest in the position, your research experience, and how your expertise aligns with the research goals of the position.

· A detailed curriculum vitae, including a list of publications.

· Contact information for two professional references.

Please forward these documents directly to Dr. M. Walczak at [Please click the Apply button for the link or email]


University of Colorado is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Applications from women, minorities, and individuals with disabilities are strongly encouraged.

Application Deadline: 2024-09-30


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