Company:  Confidential

Job Title: Postdoctoral Fellow

Job Number: 54612

Location: Charleston, US

Job Description

The de Cubas Lab in the Department of Microbiology & Immunology at the Medical University of South Carolina and the Hollings Cancer Center has an opening for a postdoctoral researcher. The de Cubas aims to understand how cancers interact with the immune system to identify molecular determinants of immunogenicity and develop strategies to modulate immunogenicity to enhance response to immune checkpoint blockade therapies. The Lab also investigates how loss of histone modifiers and chromatin remodelers (SETD2, BAP1, and PBRM1) contribute to the development and progression of cancer and developing novel therapeutic strategies based on synthetic lethality.


Operating at both wet and dry lab levels, the de Cubas Lab’s research bridges genomics and bioinformatics with translational cancer research and tumor immunology to study the complex relationship between cancer cells and the immune system. Studies will use a range of complementary methods, including among other, cellular and molecular biology (PCR, immunoblot, immunoprecipitation), microscopy, flow cytometry, single-cell sequencing, and functional in vitro and in vivo studies. The lab also has expertise in bioinformatics and computational biology.


The candidate should be highly motivated with a recent PhD degree and a solid background and skills in molecular/cell biology, biochemistry, and/or bioinformatics. Experience in mouse experimentation is desirable.

The Hollings Cancer Center (HCC) is the only NCI-Designated Cancer Center in South Carolina. Currently, HCC researchers hold approximately $45 Million in annual extramural cancer research funding with $23 Million originating from the NCI.

MUSC is located in historic Charleston, South Carolina. The weather is beautiful year-round, with temperatures rarely dropping below freezing during winter. There are several beaches within minutes of the city and the mountains are only three hours away. In addition to these amenities, the art, history, food, and festivals make Charleston an outstanding place to live.

To apply, please use the application link provided, or send a cover letter outlining your research interests and goals, CV with a list of publications, and the contact information of three references to Dr. Aguirre A. de Cubas by email ([Please click the Apply button for the link or email]).

Application Deadline: 2023-09-28


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