Postdoctoral Fellow – Humam Kadara Lab – UT MD Anderson Cancer Center

Job Title: Postdoctoral Fellow – Humam Kadara Lab – UT MD Anderson Cancer Center

Job Number: 63521

Location: Houston, US

Job Description

Program Description
Our laboratory studies ecological mechanisms in early lung cancer development and response to immune-based treatment. We seek a talented and highly motivated postdoctoral fellow with a strong background in bioinformatics and passion in exploring the heterogeneity and evolution of tumor cells and tumor microenvironment (TME) using state-of-the-art single-cell and spatial profiling approaches. The primary research focus of the candidate postdoc will be to employ innovative bioinformatics approaches to dissect in both human-relevant models of lung cancer as well as unique cohorts of human lung tissues the tumor “ecosystem” and profile in-depth phenotypic and functional heterogeneity, lineage plasticity and evolutionary dynamics of tumor and TME cells as well as cell-cell interactions in order to better understand lung cancer development, progression and therapeutic response.

Learning Objectives
Learn and master skills for in-depth profiling of single-cell sequencing and spatial transcriptomics data. Learn and master skills for integrative analysis of high-dimensional bulk and single-cell multi-omics data. Gain rich knowledge in cancer biology, cancer genomics and immunogenomics, and cancer-specific bioinformatics. Develop skills in study design, data interpretation, presentation, and manuscript writing. Develop skills in networking, career planning, teaching, grant writing, and other professional development skills that can help the candidate fellow’s career trajectory.

Eligibility and Requirements
Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g., Python) and knowledge in biostatistics are required. Experience working with single-cell sequencing data and high-performance computing environment is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.

Interested applicants should send a cover letter specifying past research experience, skills, accomplishments, and goals, as well as a curriculum vitae and the contact information for three referees to Dr. Humam Kadara ([Please click the Apply button for the link or email]) with the subject line entitled “Postdoctoral Fellow – Application – Applicant’s Name”.

Application Deadline: 2023-11-01