Job Title: POSTDOCTORAL ASSOCIATE: MOLECULAR IMMUNOLOGY IN CHICAGO
Job Number: 66659
Location: Chicago, US
POSTDOCTORAL ASSOCIATE: MOLECULAR IMMUNOLOGY IN CHICAGO
An NIH funded postdoctoral position is available immediately for a highly motivated early career scientist to study the molecular, epigenetic and genomic mechanisms regulating humoral immunity. Current NIH funded projects focus on the interface of chromatin conformation with gene expression and the functional implications of these events to immunoglobulin repertoire development and humoral immunity. The position in the Kenter laboratory at the University of Illinois College of Medicine is located in a vibrant scientific environment with cross-cutting Chicago-wide programs in molecular genetics and genomics. The candidate must have excellent training and recent research experience in molecular/cellular biology and immunology or a closely related discipline.
Our studies are focused on features promoting productive Igh locus rearrangements including chromosomal conformation, epigenetic modifications and spatial localization in 3D nuclear space in progenitor and mature B lymphocytes (see Cell Rep 14:896, Cell Rep 37:110059; Nat. Comm. 14:1225). We investigate radial positioning of gene loci in 3D nuclei as a condition of robust locus function using state of the art imaging and molecular approaches. We also examine immunoglobulin repertoire in early and mature stage B cell compartments from young and old individuals to assess the molecular underpinnings of immunosenescence that contributes to immune suppression of the elderly. We engage in collaborative mechanistic studies with other labs within our institution and nationally.
We seek highly motivated future career scientists capable of independent thinking, open to teamwork and determined to conquer new techniques. It is our mission to provide a excellent learning environment to train the next generation of scientists. The successful candidate will be provided opportunities to present their work at local and national meeting venues.
· Design and develop a range of molecular methods and projects with the Principal Investigator and collaborators.
· Conduct independent investigation, data collection and analysis.
· Optimize new methods and technologies.
· Prepare scientific results for publication in peer-reviewed journals.
· Communicate results at internal and external scientific conferences.
· Assist in the training of graduate students and research staff.
· Participate in laboratory meetings and planning
· Candidates must hold a recent PhD, MD or MD/PhD degree in immunology, molecular biology and/or biochemistry or a related field.
· Three years or less of postdoctoral experience.
· Prior experience with molecular biology.
· At least one first-authored peer reviewed paper in an international journal
· Excellent written and oral communication skills.
· Proficiency in cell culture and bioinformatics
· Analysis of primary lymphocytes and multicolor flow cytometry.
· Experience with handling mice.
Highly competitive salary and benefits commensurate with experience and NIH scale are offered.
Applicants should send a cover letter with brief description of research experience and future interests, curriculum vitae, and list of three references a single pdf file. Send the application materials to Dr. Amy L. Kenter by email: [Please click the Apply button for the link or email]
The University of Illinois at Chicago is an affirmative action, equal opportunity employer that has a strong institutional commitment to the principle of diversity and is particularly interested in receiving applications from a broad spectrum of people. We are committed to equal employment opportunities regardless of sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
Offers of employment by the University of Illinois may be subject to approval by the University’s Board of Trustees and are made contingent upon the candidate’s successful completion of any criminal background checks and other pre-employment assessments that may be required for the position being offered.
The University of Illinois System requires candidates selected for hire to disclose any documented finding of sexual misconduct or sexual harassment and to authorize inquiries to current and former employers regarding findings of sexual misconduct or sexual harassment. For more information, visit https://www.hr.uillinois.edu/cms/One.aspx?portalId=4292&pageId=1411899
Application Deadline: 2023-11-30