Company:  Confidential

Job Title: Postdoctoral associate in cell biology/DNA replication

Job Number: 69412

Location: Pittsburgh, US

Job Description

We are looking for a highly motivated postdoc with a strong background in molecular and cell biology to join the lab at the University of Pittsburgh and UPMC Hillman Cancer Center, in Pittsburgh, Pennsylvania (USA) in early 2024! Later start dates can also be considered.

DNA replication is one of the major targets of cancer therapies, as cancer cells tend to proliferate faster and are generally more prone to replication stress. Most of the information about DNA replication initiation currently comes from model organisms, such as yeast, but their applicability to human system is limited. Some of the critical steps of replication initiation are very poorly understood in human system. We use auxin-inducible degron systems, proximity labelling screens, CRISPR knock-ins, and other cell biology approaches to study replication initiation in human cells in order to exploit the findings in cancer therapies.

More about the lab:

We are looking for:
·     Ph.D. in a related discipline;
·     Strong communication skills (English), i.e., writing academic papers and giving presentations in English;
·     Proficiency in molecular and cell biology methods;
·     Good organizational skills, ability to document and analyze experiments;
·     Ability to work individually and in a team;
·     High motivation and interest in solving basic science problems;
·     Previous experience in the field of DNA replication or genome stability is preferred but not required.

We offer salary in agreement with the NIH scale, inclusive and supportive atmosphere, strong collaborative environment of the Genome Stability Program at HCC, young PI who is highly interested in your success, career development support, ability to apply for internal and external funding. International candidates will be supported to apply for US visas.

The Genome Stability Program at UPMC Hillman Cancer Center led by Dr. Ben Van Houten and Dr. Patty Opresko, gathered a large group of highly collaborative research teams working on various aspects of genome stability and DNA damage response.
University of Pittsburgh was #3 in the USA by NIH finding in 2022, in agreement with its highly competitive level in biomedical research. At the same time, Pittsburgh is consistently ranked among the best places to live in the USA, citing high quality of life, low cost of living, and younger and diverse demographic shaped by multiple Universities.

The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community. This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover, belong, contribute, and grow, while honoring the experiences, perspectives, and unique identities of all.
 The University of Pittsburgh is an Affirmative Action/ Equal Opportunity Employer and values equality of opportunity, human dignity, and diversity, EOE, including disability/vets.


If you are interested, please send me your CV and a brief cover letter by email 

Application Deadline: 2023-12-31


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