Job Title: NeuroAI Research Intern
Job Number: 69892
Location: Cold Spring Harbor, NY, USA, US
The laboratory of Dr. Christopher Vakoc at Cold Spring Harbor Laboratory seeks to hire a Postdoctoral Fellow to lead a project focused on cancer epigenetics and lineage plasticity. The key requirement for this position is recent Ph.D. training in cancer biology, cell biology, molecular genetics, or epigenetics. Familiarity with cancer models (tissue culture and/or animal), CRISPR-based genetic perturbations, and genome-scale evaluations of chromatin would be the most relevant for this position, however exceptional candidates will be considered with any area of biological research expertise. Candidates from non-traditional and/or under-represented backgrounds are strongly encouraged to apply.
The Vakoc lab studies transcriptional mechanisms that drive the pathogenesis of the cancer, with broad interests in the areas of leukemia, sarcoma, pancreatic, and lung cancers. A key enabling technology for this research is high-throughput genetic screening, which they have used to discover novel master regulators of tumor cell identity and novel therapeutic targets that allow for reprogramming of tumor cell identity. This postdoc hire will lead a new independent project that seeks to make an impactful discovery in the broad research area of cancer epigenetics, which will be an ideal project for launching an independent academic career.
More information about the Vakoc lab can be found here: https://vakoclab.labsites.cshl.edu
A representative publication from our lab:
Wu XS, He XY, Ipsaro JJ, Huang YH, Preall JB, Ng D, Shue YT, Sage J, Egeblad M, Joshua-Tor L, Vakoc CR. OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 607(7917):169-175 (2022).
EDUCATION: Successful applicants will possess a Ph.D. degree in Biological Research
Experience/Skill: A background in several of the following areas would be needed for this position: DNA cloning, mammalian tissue culture, mouse genetics, ChIP-seq, CUT&RUN, RNA-seq, CRISPR-Cas9 genome editing, protein biochemistry, and computational genomics.
Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program. We believe that science is for everyone. We have had researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.
Compensation & Benefits
Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, paid time off, and a range of recognition and wellness programs. Visit our CSHL Benefits , Postdoctoral Landing sites to learn more. The salary range and/or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity). The salary for the role is $70,000 per annum.
We strongly recommend to be fully vaccinated for COVID-19 however; it is not a requirement for employment.
CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor
Application Deadline: 2024-05-15