Job Title: In vivo analysis of Mtb interactions with host cell inflammasome
Job Number: 67887
Location: College Park, US
The Briken lab (https://vbriken.wixsite.com/brikenlab ) is recruiting a postdoc to work on the interaction of M.tuberculosis with the host cell inflammasome using the mouse model of tuberculosis. This work is in continuation of previously published results ( https://doi.org/10.1371/journal.ppat.1009712) where we show that a protein kinase of Mtb is important for inhibiting NLRP3 inflammasome activation. The project aims at characterizing the molecular mechanisms of NLRP3 inflammasome inhibition and the impact on in vivo virulence. The preferred candidate should have experience with mouse work (especially lung biology). Experience working with Mtb is desired but not required. Starting salary of >$60K depending on experience and qualifications.
Application Deadline: 2023-11-30