1-617-500-6690 [email protected]

Exo Therapeutics

Job Title: Executive/Senior Director, Discovery Biology

Job Number: 30598

Location: 480 Arsenal Way Watertown, MA 02472

Job Description

Exo Therapeutics seeks a strong leader to lead our Discovery biology efforts and provide strategic and technical expertise for Exo’s research portfolio. You will be an integral part of the biology leadership team, working cross functionally to drive cutting-edge research – with an initial focus in Oncology/Autoimmune diseases. You will be responsible for decision-making and driving the biology efforts to support drug discovery. You will guide the design and execution of assays and mechanistic experiments to support the preclinical evaluation of chemical matter from hit ID to IND nomination. To do this, you will build and mentor a team of discovery biologists and develop them as project leaders. You will also work closely with key collaborators and outside contract organizations and have highly visible opportunities to interface with all levels of our organization to deliver scientific excellence, as we expand the boundaries of research for patients.

Responsibilities

  • Be an integral member of planning and prioritization of biology strategy and workflows across our portfolio
  • Support drug discovery from HitID to IND nomination, work with cross functional leads to create and execute on research strategies for discovery programs to enable clear go-no/go decisions and timelines
  • Oversee the development and execution of assays and mechanism of action studies to understand the biological behavior of chemical matter
  • Direct, manage, develop, and empower a team of internal and external scientists in Discovery biology; outline and communicate research goals
  • Manage relationships with external CROs focusing on preclinical mechanism of action studies, compound screening, reagent generation, assay development/validation and computational biology activities
  • Communicate and present progress updates to key decision makers including partners, team, BOD, and management team

Required Skills

  • Ph.D. in Biological sciences, with 10+ years in biotech/ pharmaceutical industry
  • Strong track record of being a project leader and delivering clinical candidates
  • A Proven track record of experience across multiple stages of drug discovery, from target selection to IND-filing, preferably in oncology drug discovery
  • Expertise in design of assays and criteria for evaluating molecules at each stage of drug discovery
  • Strong understanding of cancer cell signaling pathways/ inflammation/ autoimmunity
  • Ability to successfully participate in a highly creative and enthusiastic start-up environment

All fully qualified applicants who are authorized to work in the US at the time of application will receive consideration for employment without regard to race, religion, gender, sexual orientation, national origin, ancestry, disability, veteran status, as protected under law.

 

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