Seres Therapeutics

Job Title: Bioprocess Development Scientist

Job Number: 22957

Location: Cambridge, MA

Job Description

Seres is seeking a Bioprocess Development Scientist to join our dynamic and strong performing team to help develop and establish microbial fermentation processes for our candidate therapies. This position reports directly to the Director, Bioprocess and would provide critical development of upstream and downstream manufacturing processes for candidate microbiome therapies. This individual will demonstrate these manufacturing processes at pilot scale for the production of pre-clinical supplies. Success in the role will require prior experience with upstream or fermentation engineering problems in bacteria, yeast, mammalian cells, or other organisms. Our collaborations with scientific, pre-clinical, manufacturing, and regulatory affords the group the opportunity to learn about the whole drug development process, and to contribute in shaping our overall strategy.


  • Developing upstream and downstream manufacturing processes, including new platform operations for the bioprocessing of strict anaerobic bacteria
  • Scale-up/scale-down process design to link bench-scale development to pilot and manufacturing scales
  • Ownership to propose experimental designs, and hands-on lead for experiments
  • Data analysis for development of Process Control Strategy for critical operations
  • Discovery and development of Process Analytical Technologies (PAT) in cooperation with Analytical Development teams
  • Tech transfer of processes to Seres internal Manufacturing groups
  • Authoring of SOPs, reports and Regulatory documentation
  • Presentation of results to senior CMC Leadership

Required Skills

  • MS/Ph.D. in fermentation engineering, chemical engineering, or related field with +2-5 years of academic/industrial experience
  • Demonstrated success taking on tough challenges when developing fermentation technology
  • Exposure to various analytical methods in order to develop new manufacturing techniques
  • Strong track record of effective communication when presenting results by both oral presentation and written publication


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