Bioinformatic Research Scientist in Cancer Genomics and/or Metabolomics

Job Title: Bioinformatic Research Scientist in Cancer Genomics and/or Metabolomics

Job Number: 65651

Location: Memphis, US

Job Description

A Bioinformatic Research Scientist position is available in the lab of Dr. Jian Xu at Department of Pathology and Center of Excellence for Leukemia Studies (CELS) at St. Jude Children’s Research Hospital to study the genomic and/or metabolic mechanisms controlling stem cell development and blood cancers.

Our lab uses cutting-edge genomics, metabolomics and bioinformatics approaches in a multi-disciplinary and collaborative team setting. Our recent studies include the development of the CRISPR CAPTURE approach (Cell 170:1028), the analysis of rewired BCAA metabolism (Cancer Discovery 9:1228), the role of pathogenic non-coding variants (Cancer Discovery 10:724), retrotransposon silencing (Nature Genetics 53:672), and therapy resistance (Cancer Discovery 13:170) in hematologic malignancies.

The main responsibilities will be developing and implementing bioinformatic methodologies for integrative genomic and metabolomic studies of childhood cancers; overseeing operations related to genomic and metabolomic data processing and analysis within the Advanced Technology & Genomics (ATG) core, including software pipelines for short-reads and long-reads-based genome sequencing, high throughput metabolomic profiling, and stable isotope tracing; managing databases; and providing bioinformatic support and services to other lab members and St Jude researchers.

Candidates must hold a MS or PhD degree with a strong background in genomics, metabolism research, and/or cancer biology. Interested individuals should upload a CV, a short summary of research interest and experience, and a list of three references.

Application Deadline: 2024-02-29