1-617-500-6690 [email protected]

Job Title: Director or Associate Director Discovery

Job Number: 31179

Location: North Cambridge, MA 02139

Job Description

Carmine is seeking a Director of Discovery to lead a rapidly growing drug discovery team developing a novel gene therapy platform. This individual will have broad leadership responsibilities to drive our gene delivery platform optimization and drug discovery programs.


  • Build and lead a discovery team to optimize RBCEV gene delivery platform and establish discovery pipeline programs.
  • Drive strategic decisions on discovery and interface with scientists and senior leaders through effective communications.
  • Explore and implement innovative ideas and technologies for platform optimization, target selection, and product characterization.
  • Oversee drug discovery programs through lead identification, lead optimization, and IND enabling studies and deliver targeted goals and timelines.
  • Reinforce ELN documentation, laboratory best practices, and intellectual property expansion. 
  • Partner with Molecular Biology and CMC teams to advance pipeline discovery and platform innovation

Required Skills

  • PhD in Biology a related field and 5+ years of related experience including 3+ years of team or project leadership
  • Experience managing a team in drug discovery or platform innovation
  • Ability to collaborate with scientists and leadership across diverse areas of expertise
  • In-depth experience in disease biology, gene therapy, nucleic acid delivery, or extracellular vesicles is a strong plus.
  • The level of the role will be commensurate with the education, years and relevance of experience of the identified candidate.


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